Editorial overview: Tumour immunology: What's beyond today's success in tumor immunology
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چکیده
منابع مشابه
Tumor Immunology, toward a Success Story?
PROOF OF IMMUNOSURVEILLANCE AND THE IMMUNOEDITING CONCEPT The beginning of the second millennium marked a turning point for tumor immunity, on the basis of a series of data obtained in mice and in humans. The enhanced susceptibility of immunodeficient mice to the formation of chemically induced or spontaneous tumors clearly showed that the immune system can eliminate nascent tumors (1). A few y...
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Malignant tumors express antigens that may stimulate and serve as targets for antitumor immunity. Virally induced tumors usually contain integrated proviral genomes in theircellulargenomes and often express viral genome-encoded proteins that may stimulate specific host immune responses. Antigens unique to individual tumors that stimulate specific rejection of transplanted tumors have been demon...
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The immune system is characterized by the ability to distinguish self from non-self. The intestinal immune system bears this latter property but, furthermore, it must discriminate among nutritious and beneficial substances from toxic or harmful ones. Considering that the gut has to be colonized by commensal bacteria participating in digestion as well as in the control of pathogen microorganisms...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2016
ISSN: 0952-7915
DOI: 10.1016/j.coi.2016.02.002